Example of Asset Evaluation-Journal Course

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This research study compared the use of mepivacaine 2% and isobaric bupivacaine 0.5% as spinal anesthetics in patients undergoing total knee arthroplasty (TKA) procedures. The study aimed to assess specific intraoperative and postoperative outcomes such as heart rate, blood pressure, use of vasopressors, fluid resuscitation, postoperative pain scores, opioid analgesic use, and time to ambulation. The results showed that patients receiving mepivacaine 2% had greater hemodynamic stability during the first 30 minutes after anesthetic administration compared to those receiving isobaric bupivacaine 0.5%. They also required less opioid medication for postoperative pain management and were able to ambulate sooner after the procedure. Overall, mepivacaine 2% was found to be the higher-performing local primary spinal anesthetic for patients undergoing TKA. The study suggests that mepivacaine 2% provides an adequate block for the surgical procedure, maintains hemodynamic stability, and offers a faster time to ambulation, which can contribute to same-day discharge for TKA patients. This research highlights the importance of considering the type and dosage of spinal anesthetics in order to improve patient outcomes and optimize cost-effective care.

Keywords

mepivacaine 2%

isobaric bupivacaine 0.5%

spinal anesthetics

total knee arthroplasty

intraoperative outcomes

postoperative outcomes

hemodynamic stability

opioid analgesic use

time to ambulation

same-day discharge